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benefits over random integration
Meganuclease-driven targeted integration is fast, effortless, and guarantees controlled gene expression
Unless classical stable transfection which gives rise to random and uncontrolled integration events, meganuclease-driven targeted integration achieves:
- efficient integration (10-3 to 10-4 integration events from the starting cell population)
- guaranteed gene expression at the targeted locus
- homogeneous protein production thanks to single copy integration