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Custom TALEN® Service

Custom TALEN® Service

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>>> Check out now if your sequence's got talent: use our TALEN® Hit™ software.


> TALEN®  Services

  • TALEN® Access and TALEN® First: Production of Custom TALENs® for all gene customization projects: to target any gene, at any position, in any genome.
  • NEW!!! TALEN® Sure KO™: TALEN® Sure KO™ ensures gene knock-out by introducing frame shift mutations with the first coding exon of any gene.
  • Custom TALEN® Project Support: Project-specific, personalized scientific support for the highest project success.

 

Products Information:

> TALEN® Access

  • Submission by customer of target sequence
  • Engineering of a Custom TALEN® cleaving customer's target. A functional TALEN® is defined as a heterodimer (2 units of a Transcription Activator-Like Effector fused to a catalytic domain).
  • Validation of the Custom TALEN® cleavage activity on episomal target sequence (assay performed in yeast)
  • Custom TALEN® delivered in a pair of expression plasmids (each containing one unit) for mammalian expression, mRNA synthesis or promoter cloning
  • TALEN® sequence verified
  • Cleavage activity results

Delivery timeframe

Within 8 weeks after purchase order reception and sequence submission

Limitation of Use

Research Use Only (RUO)

Price

€ 5,000 / USD 5,000

 

> Order now!

 

 

> TALEN® First

The TALEN® First  offer includes the TALEN®  Access  deliverables and the validation of the Custom TALEN® cleavage activity on chromosomal target sequence.

Delivery timeframe

Within 9 weeks after purchase order reception and sequence submission

Limitation of Use

Research Use Only (RUO)

Price

€ 10,000 / USD 10,000


> Order now!

 

 

> !!! NEW !!! TALEN® Sure KO™

  • Submission by customer of target sequence
  • Engineering of a TALEN® Sure KO™ specifically designed for disrupting the first coding exon of any gene
  • Validation of the TALEN® Sure KO™ cleavage activity on episomal target sequence (assay performed in yeast)
  • TALEN® Sure KO™ delivered in a pair of expression plasmids (each containing one unit) for mammalian expression, mRNA synthesis or promoter cloning
  • TALEN® Sure KO™ sequence verified
  • Cleavage activity results

Delivery timeframe

Within 8 weeks after purchase order reception and sequence submission

Limitation of Use

Research Use Only (RUO)

Price

€ 5,000 / USD 5,000

 

> Order now!

 


> Custom TALEN® Project Support

We provide, with a scientist (Ph.D.), expertise in genome customization. Our project manager from Cellectis bioresearch will help you to better define the best Custom TALEN® fitted to you genome customization project.

For an additional cost, we can also provide you with the tools to acheive your project goals (creating the integration or conversion matrix to be used for introducing your desired targeted modifications).

We will provide support for all questions concerning the choice of the best Custom TALEN® hits, the choice of the vector to deliver the Custom TALEN® into your cells, the design of the integration or conversion matrix and the transfection conditions.

Support for targeted modification projects include:

  • Nucleotide substitutions;
  • Targeted integration;
  • Gene knockouts;
  • Gene tagging;
  • Promoter swapping

Price

€ 1,000 / USD 1,500


> Order now!

 

  > To enquire about the Custom TALEN® service, feel free to contact us.


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