Publications

Meganuclease-mediated Inhibition of HSV1 Infection in Cultured Cells

Grosse S, Huot N, Mahiet C, Arnould S, Barradeau S, Clerre DL, Chion-Sotinel I, Jacqmarcq C, Chapellier B, Ergani A, Desseaux C, Cédrone F, Conseiller E, Pâques F, Labetoulle M, Smith J.

Mol Ther. 2011 Jan 11. (Epub ahead of print)

Meganucleases and other Tools for Targeted Genome Engineering: Perspectives and Challenges for Gene Therapy

Silva G, Poirot L, Galetto R, Smith J, Montoya G, Duchateau P, Pâques F.
Curr Gene Ther. 2010, Dec 24 (Epub ahead of print)

The I-CreI meganuclease and its engineered derivatives: applications from cell modification to gene therapy

Arnould S, Delenda C, Grizot S, Desseaux C, Pâques F, Silva GH, Smith J.
Protein Eng Des Sel, 2010. Nov 3. [Epub ahead of print]

Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus

Muñoz IG, Prieto J, Subramanian S, Coloma J, Redondo P, Villate M, Merino N, Marenchino M, D'Abramo M, Gervasio FL, Grizot S, Daboussi F, Smith J, Chion-Sotinel I, Pâques F, Duchateau P, Alibés A, Stricher F, Serrano L, Blanco FJ, Montoya G.

Nucleic Acids Res. 2010 Sep 16.

Meganuclease-Driven Targeted Integration in CHO-K1 Cells for the Fast Generation of HTS-Compatible Cell-Based Assays

Jean-Pierre Cabaniols, Christine Ouvry, Véronique Lamamy, Isabelle Fery, Marie-Laure Craplet, Natacha Moulharat, Sophie-Pénélope Guenin, Stéphane Bedut, Olivier Nosjean, Gilles Ferry, Séverine Devavry, Cécile Jacqmarcq, Céline Lebuhotel, Luc Mathis, Christophe Delenda, Jean A. Boutin, Philippe Duchâteau, Francis Cogé, and Frédéric Pâques

Published online before print July 12, 2010, doi: 10.1177/1087057110375115

Meganucleases can restore the reading frame of a mutated dystrophin

P. Chapdelaine, C. Pichavant, J. Rousseau, F. Pâques and J.P. Tremblay
Gene Therapy (2010) 17, 846–858; doi:10.1038/gt.2010.26; published online 15 April 2010

Targeted gene modifications in drug discovery and development

Jean-Pierre Cabaniols, Luc Mathis and Christophe Delenda
Curr Opin Pharmacol. 2009 Oct;9(5):657-63. Epub 2009 Jun 12.

Generation of redesigned homing endonucleases comprising DNA-binding domains derived from two different scaffolds

S. Grizot, J.C. Epinat, S. Thomas, A. Duclert, S. Rolland, F. Pâques, P. Duchateau
Nucleic Acids Res. 2010 Apr;38(6):2006-18. Epub 2009 Dec 21.

Targeted approaches for gene therapy and the emergence of engineered meganucleases

R. Galetto, P. Duchateau and F. Pâques
Expert Opinion on Biological Therapy October 2009, Vol. 9, No. 10, Pages 1289-1303

Reduced immunoglobulin class switch recombination in the absence of Artemis

P. Rivera-Munoz, P. Soulas-Sprauel, G. Le Guyader, V. Abramowski, S. Bruneau, A. Fischer, F. Pâques, J.-P. de Villartay
Blood, 22 October 2009, Vol. 114, No. 17, pp. 3601-3609.

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