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cGPS® System

Find your way in pre-engineered cell lines
Kits for fast and effortless gene integration at a given engineered locus

Meganucleases are natural enzymes from yeast, bacteria, algae and fungi that recognize and cleave at unique positions in the genomic DNA of their originating hosts.

Meganucleases induce DNA double-strand breaks that can be repaired using natural homologous recombination.

We have introduced the recognition site of a natural meganuclease in the genome of the most common mammalian cell lines. These pre-engineered cell lines can achieve targeted integration when used in combination with a natural meganuclease and a repair matrix that contains the gene of interest (GOI).

  • optimal gene integration efficiency
  • guaranteed gene expression
  • sustained protein production
  • clone homogeneity
  • fast & effortless

cGPS® is the most efficient way to stably express a protein from the most common cell lines!