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Custom TALEN™ Services
Cellectis bioresearch is your preferred provider for TALEN™ Services
We offer the best suited Custom TALEN™ in combination with the validation level of your choice to succeed in your specific gene editing projects:
- add genetic diversity
- add reporters or tags
- create gain and loss of function mutations
- knock-out a gene function efficiently
- knock-out and transgenic animals
- add any other modification to your immortalized and iPS cell lines.
We provide Custom TALEN™ design, synthesis, validation and support, to optimize success rates of all your gene editing projects.
Would you like more information? Contact us!
You can combine every gene editing project specific Custom TALEN™ with the validation level of your choice!
| gene editing project specific TALEN™ | |||
| TALEN™ Basic | TALEN™ Sure KO | TALEN™ CpG | |
| definition | suitable for any gene editing project | designed to introduce frame shift mutations within the 1st coding exon of any gene | designed to overcome the impact of methylated DNA on TALEN™ nuclease activity |
| validation level | ||||
| Access | First | Premium | ||
| definition | the standard validation for all species other than human | the standard validation for human cell lines | validation on request for mouse & rat cell lines | validation on request for customers' cell lines* |
| validation method | of sequence specific TALEN™ activity on a episomal target | of sequence specific mutagenesis activity on chromosomal target | of sequence specific mutagenesis activity on chromosomal target | of sequence specific mutagenesis activity on chromosomal target |
| SSA yeast assay | deep sequencing | deep sequencing | deep sequencing | |
| deliverables | 1 TALEN™ + validation report | up to 2 TALEN™ + validation report | all validated TALEN™ + validation report | all validated TALEN™ + validation report |
| TALEN™ delivery timelines | 4 weeks** | 4 weeks** | 9 weeks | 12 weeks |
* immortalized cell lines
** additional 4 weeks for validation report
Custom TALEN™ Services come with:
- Standard validation of the sequence specific TALEN™ activity.
- Rigorous quality control: RVDs systematically sequenced after TALEN™ assembly
- Optimal design: thanks to proprietary TALEN™ Hit software and expert know-how
For all Custom TALEN™ Services, we offer Custom TALEN™ Project Support, a comprehensive service for TALEN™ project optimization:
Contact your local sales representative to discuss your gene editing project in detail and request an official quote.
- Custom TALEN™ Project Support: comprehensive service for TALEN™ project optimization. Cellectis bioresearch provides a dedicated project support managers who will share with you competence and know-how to define the best Custom TALEN™ suited to your genome customization project.