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CanCELL
CanCELL cell lines represent comprehensive knock–out of the major disease relevant oncogenes and tumor suppressor genes (TSG).
Benefits:
Comparable results |
Convenient and flexible |
Reliable cell model |
True isogeny:All knock-out mutants are derived from the same parental cell line - comparable results between parental and knock-out cell line for improved interpretation |
Suitable for in vitro and in vivo studies:Allows you to keep track of your results when changing from in vitro to in vivo - for increased productivity |
STR analyzed:Authentication and certification of parental and gene edited cell lines |
They offer unparalleled opportunities to study signaling pathways, gene function and develop functional assays in a common genetic background, for example:
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evaluate the relationship between drug efficacy and pathway activation / inactivation
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or set-up primary screens (siRNA, shRNA, drug candidates) for identification of synthetic lethal interactions
CanCELL represents cancer disease relevant gene selection:
CanCELL cell lines are generated by utilizing our proprietary TALEN™ technology.
CanCELL tailor–made panel can be available and extended on demand.
For further specific needs take a look at our Cell line Customization Services.