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Gene modification: TALEN™ Basic
Your Custom TALEN™ of choice for any gene modification project
TALEN™ Basic is your Custom TALEN™ of choice for any gene modification projects. You can tag genes, swap promoters or substitute nucleotides.
Validation of your choice
TALEN™ Basic’s activity can be validated at the level of your choice (no validation, on episomal or chromosomal target sequence). We offer standard validation levels for human, mouse & rat cell lines, as well upon request validate the TALEN™ activity on your cell line. Talk to us about your TALEN™ project and let us define the best TALEN™ for your project.
See below the different validation levels:
validation level |
|||||
No validation |
Access |
First human |
First mouse & rat |
Premium |
|
| definition | TALEN™ without validation | validation on request | the standard validation for human cell lines | validation on request for mouse & rat cell lines | validation on request for customers' cell lines |
|
validation method |
- | of sequence specific TALEN™ activity on a episomal target | of sequence specific mutagenesis activity on chromosomal target | of sequence specific mutagenesis activity on chromosomal target | of sequence specific mutagenesis activity on chromosomal target |
| - | SSA yeast assay | deep sequencing | deep sequencing | deep sequencing | |
| deliverables | 2 TALEN™ | 1 TALEN™ + validation report | 2 TALEN™ + validation report | all validated TALEN™ + validation report | all validated TALEN™ + validation report |
|
TALEN™ delivery timelines |
4 weeks | 4 weeks** | 4 weeks** | 9 weeks** | 12 weeks** |
*immortalized cell lines
**additional 4 weeks for validation report
Find below a list of our TALEN™ Basic options:
| Product name | Validation level | Cat No. |
|---|---|---|
| TALEN™ Basic | No validation | TALEN-BA-NV-RCT |
| TALEN™ Basic - Access | Access | TALEN-BA-ACC-RCT |
| TALEN™ Basic - First human | First human | TALEN-BA-FRH-RCT |
| TALEN™ Basic - First mouse & rat | First mouse & rat | TALEN-BA-FRMR-RCT |
| TALEN™ Basic - Premium | Premium | TALEN-BA-PRE-RCT |
Specific solutions for methylated DNA and knock-out
Do you have other gene editing projects in mind? Learn more on TALEN™ CpG to edit methylated DNA or on TALEN™ Sure KO to ensure knock-out with the 1st coding exon of your gene of interest.
Custom TALEN™ project support
For any of your gene editing projects, we offer Custom TALEN™ Project Support, a comprehensive service for TALEN™ project optimization. Comes with dedicated project support managers who will share with you competence and know-how to define the best Custom TALEN™ suited to your genome customization project.