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Hepatocytes
Effective tools for the in vitro evaluation of chronic hepatotoxicity
hES-HEP™ and hiPS-HEP™ are highly homogenous populations of human ES- and iPS-derived hepatocytes. The cells are ideal for use in hepatocyte-related applications that demand a highly reproducible platform and continuous supply of material. Our hepatocytes will help you deliver consistent and predictable results in your long term toxicity studies.
hiPS-HEP™ (human iPS-derived cells)
| Reference | Format | Size | Quantity |
|---|---|---|---|
| HEP-103-VIAL-01 | Frozen | 1 vial suitable for one 96-well plate | >7x106 cells |
| HEP-103-0024 | Fresh | 24-well plate | 3.3x106 cells |
| HEP-103-0096 | Fresh | 96-well plate | 2.0x106 cells |
hES-HEP™ (human ES-derived cells)
| Reference | Format | Size | Quantity |
|---|---|---|---|
| HEP-102-0006 | Fresh | 6-well plate | 4.3x106 cells |
| HEP-102-0024 | Fresh | 24-well plate | 3.3x106 cells |
| HEP-102-0096 | Fresh | 96-well plate | 2.0x106 cells |
| HEP-102-0T25 | Fresh | T25 flask | 1.9x106 cells |
Benefits
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Long-term toxicity studies
- stable CYP1A & 3A activity for up to 8 days (post-recovery) suitable for metabolic toxicity and chronic toxicity
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Relevant & predictive toxicology data
- humanES- and iPS-derived cells with expression of main hepatotoxicity markers
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Reproducibility
- low lot-to-lot variation (<20%)
- robust differentiation protocols resulting in highly homogenous population (>80% pure)
- continuous supply of material from a consistent genetic background
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Flexibility
- fresh and frozen format
- available in vial, multi-well plate format and T25 format
| Applications | Typical assays |
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