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Fresh and frozen hiPS-HEP™
Relevant models for in vitro toxicology
Our hiPS-derived hepatocytes are ideal for the in vitro evaluation of hepatotoxicity delivering consistent and predictable results in your long term toxicity studies.
Product Information:
| Reference | Format | Size | No. of cells |
|---|---|---|---|
| HEP-103-VIAL-01 | Frozen | 1 vial suitable for one 96-well plate | >7x106 |
| HEP-103-0024 | Fresh | 24-well plate | 3.3x106 |
| HEP-103-0096 | Fresh | 96-well plate | 2.0x106 |
| Characteristics | Assay | Analyte | At delivery | 8 Days post delivery |
|---|---|---|---|---|
| CYP-activity | LC-MS | CYP3A-activity | + | + |
| CYP1A-activity | + | + | ||
| Transporter activity | TCA uptake | NTCP | + | + |
| Protein markers | ICC | a-1-antitrypsin | + | + |
| Albumin | + | + | ||
| HNF4a | + | + | ||
| CK18 | + | + | ||
| GSTA1 | + | + | ||
| OCT4 | - | - | ||
| Gene expression | QPCR | a-1-antitrypsin | + | + |
| HNF4a | + | + | ||
| GSTA1 | + | + | ||
| OCT4 | - | - | ||
| Capability to store glycogen | PAS | Glycogen | + | + |