Mesenchymal progenitors derived from hESC, a homogeneous and robust source for in vitro use in research applications.

hES-MP™002.5 are hES cell-derived mesenchymal progenitors proven to have a high resemblance to adult human mesenchymal stem cells (hMSCs). The cells can be differentiated towards several mesodermal lineages. The hES-MP™002.5 are specifically efficient for the differentiations towards the osteogenic lineage and have a high mineralization potential after protracted culture. The cells are delivered frozen in a single cell suspension.

The hES-MP™002.5 are an ideal platform for bulk production of mesenchymal cells where a homogeneous, robust and unlimited source of cells is needed.

  • Homogenous and easy to culture cells enabling you to quickly get cells for multiple experiments;
  • Provides a model for the study of mesodermal differentiation with a high resemblance to adult mesenchymal stem cells;
  • Provides a model for the study of bone formation.

Our mesenchymal progenitors have various applications such as:

  • Mesenchymal induction and differentiation studies;
  • Tissue engineering models for repair and regeneration.

Cell doublings of hMSCs compared to hES-MP™00.5

 

Hierarchical clustering of genes with an FC ≥ 20, showing a similar gene expression pattern in hES-MP™002.5 and hMSCs

 

Table of characteristics

Osteogenic differentiation Positive von Kossa staining (mineralization)
Flow cytometry analysis
CD166 +
CD105 +
CD13 +
CD10 +
CD133 -
CD117 -

 

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